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RESERPINE

9 - Miscellaneous hazardous material
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The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 50-55-5
DOT Hazard Label USCG CHRIS Code
  • Class 9
none
NIOSH Pocket Guide International Chem Safety Card
none none
NFPA 704
data unavailable
General Description
PHYSICAL DESCRIPTION: White or cream to slightly yellow crystals or crystalline powder. Odorless with a bitter taste. (NTP, 1992)

The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
none
Air & Water Reactions
Insoluble in water. Reacts slowly with air and water. Darkens slowly on exposure to light.
Fire Hazard
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health Hazard
SYMPTOMS: Symptoms of exposure to this compound may include lowered blood pressure, sedation, bradycardia, drowsiness, nasal congestion, weight gain and severe mental depression which may lead to suicide. Other symptoms include lethargy, vertigo, gastrointestinal upset, dyspnea, flushing and parkinsonism. It can cause nightmares and an increase in gastrointestinal tone and motility with abdominal cramps and diarrhea. It can also cause insomnia, cardiotoxic effects (such as premature ventricular contractions and other arrhythmias, possible sensitization to digitalis, fluid retention and congestive failure), fatigue, weakness, excitement, irrational behavior and sodium retention edema. Exposure can cause dryness of the mouth, pruritus and skin rashes, angina-like syndrome, blurred vision, breast engorgement and galactorrhea, impotence, epistaxis, difficulty in micturition, purpura, bronchospasm, thrombocytopenia, effects on the endocrine system, interference with color vision, hematemesis, systemic lupus erythematosus and breast cancer. Exposure can also cause an increase in appetite, anxiety, headache and disturbance of ejaculation. Other symptoms include nausea with anorexia, excessive salivation, reduction in emotional tension, sleepiness, dizziness, apathy, confusion, restlessness, hallucinations, vomiting, excessive secretory and motor activity of the stomach (which may eventually lead to the formation of peptic ulcer with pain, hemorrhage and perforation), blockade of peripheral adrenergic nerves (which may cause peripheral vasodilatation), motor disturbances (apparently of the extrapyramidal system characterized by stiffness with aching pain in the legs, tremors and various types of dystonia and catatonia), hypothermia, cardiovascular collapse and coma with blushing. Chronic exposure may cause hormonal disturbances, notably mild feminization of adult males with gynecomastia and lactation. Anginal pain and extrasystoles have occurred. Psychotropic effects have also occurred. Eyes may appear slightly flushed due to the dilation of conjunctival blood vessels. Lacrimation, slight miosis and ocular spasms may occur. Eye effects also include conjunctival hyperemia. This chemical may cause serious respiratory problems in infants born to mothers exposed to it during pregnancy. Intramuscular or intravenous injection may cause postural hypotension and duodenal ulcers.

ACUTE/CHRONIC HAZARDS: This compound is highly toxic by ingestion. It is harmful if inhaled or absorbed through the skin. It may cause irritation. When heated to decomposition it emits toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides. (NTP, 1992)
Reactivity Profile
RESERPINE is a weak base and can form salts with strong acids. Incompatible with oxidizing agents and reducing agents.
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
Excerpt from ERG Guide 171 [Substances (Low to Moderate Hazard)]:

As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Firefighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Non-Fire Response
SMALL SPILLS AND LEAKAGE: If a spill of this chemical occurs, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with acetone and transfer the dampened material to a suitable container. Use absorbent paper dampened with acetone to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should protect this chemical from exposure to light. Keep the container tightly closed under an inert atmosphere, and store under refrigerated temperatures. (NTP, 1992)
Protective Clothing
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds The information in CAMEO Chemicals comes from a variety of data sources.
Chemical Formula:
  • C33H40N2O9
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: 507 to 509 ° F (decomposes) (NTP, 1992)
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity: data unavailable
Boiling Point: data unavailable
Molecular Weight: 608.7 (NTP, 1992)
Water Solubility: less than 1 mg/mL at 72┬░ F (NTP, 1992)
Ionization Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

No PAC information available.

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Department of Homeland Security's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
EPCRA 302
EHS TPQ
EPCRA 304
EHS RQ
CERCLA RQ EPCRA 313
TRI
RCRA
Code
CAA 112(r)
RMP TQ
Reserpine 50-55-5 5000 pounds U200

(EPA List of Lists, 2015)

DHS Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • ABESTA
  • ABICOL
  • ADELFAN
  • ADELPHANE
  • ADELPHIN
  • ALKARAU
  • ALKASERP
  • ALSERIN
  • ANQUIL
  • APOPLON
  • APSICAL
  • ASCOSERP
  • AUSTRAPINE
  • BANASIL
  • BANISIL
  • BENAZYL
  • BENDIGON
  • BENZ[G]INDOLO[2,3-A]QUINOLIZINE, YOHIMBAN-16-CARBOXYLIC ACID DERIV.
  • 3-BETA,20-ALPHA-YOHIMBAN-16-BETA-CARBOXYLIC ACID, 18-BETA-HYDROXY-11,17-ALPHA-DIMETHOXY-, METHYL ESTER, 3,4,5-TRIMETHOXYBENZOATE (ESTER)
  • 3BETA,20ALPHA-YOHIMBAN-16BETA-CARBOXYLIC ACID, 18BETA-HYDROXY-11,17ALPHA-DIMETHOXY- METHYL ESTER 3,4,5-TRIMETHOXYBENZOATE (ESTER)
  • 3BETA,20ALPHA-YOHIMBAN-16BETA-CARBOXYLIC ACID, 18BETA-HYDROXY-11,17ALPHA-DIMETHOXY-, METHYL ESTER, 3,4,5-TRIMETHOXYBENZOATE
  • BIOSERPINE
  • BRINDERDIN
  • BRISERINE
  • BUTISERPAZIDE-25
  • CARDIOSERPIN
  • CARDITIVO
  • CARPACIL
  • CARRSERP
  • CRYSTOSERPINE
  • DAREBON
  • DESERPINE
  • DIUPRES
  • EBERPINE
  • EBSERPINE
  • ELFANEX
  • ELSERPINE
  • ENIPRESSER
  • ENT 50146
  • ESCASPERE
  • ESERPINE
  • ESKASERP
  • GAMMASERPINE
  • GILUCARD
  • H 520
  • HELFOSERPIN
  • HEXAPLIN
  • HIPOSERPIL
  • HISERPIA
  • HYDROMOX R
  • HYDROPRES
  • HYPERCAL B
  • HYPERTANE FORTE
  • HYPERTENSAN
  • IDOSERP
  • INTERPINA
  • KITINE
  • KLIMANOSID
  • LEMISERP
  • LOWESERP
  • MARNITENSION SIMPLE
  • MAVISERPIN
  • MAYSERPINE
  • MEPHASERPIN
  • METATENSIN
  • METHYL 11,17ALPHA-DIMETHOXY-18BETA-(3,4,5-TRIMETHOXYBENZOYLOXY)-3BETA,20ALPHA-YOHIMBANE-16BETA-CARBOXYLATE
  • METHYL O-(3,4,5-TRIMETHOXYBENZOYL)RESERPATE
  • METHYL RESERPATE 3,4,5-TRIMETHOXYBENZOATE (ESTER)
  • METHYLRESERPATE 3,4,5-TRIMETHOXYBENZOIC ACID
  • METHYLRESERPATE 3,4,5-TRIMETHOXYBENZOIC ACID ESTER
  • MODENOL
  • NAQUIVAL
  • NCI-C50157
  • NEMBUSERPIN
  • NEO-SERP
  • NEOSERFIN
  • NEOSLOWTEN
  • ORTHOSERPINA
  • PERSKLERAN
  • PRESSIMEDIN
  • PURSERPINE
  • QUIESCIN
  • R-E-S
  • RAU-SED
  • RAUCAP
  • RAUDIXIN
  • RAUGAL
  • RAULEN
  • RAULOYDIN
  • RAUMORINE
  • RAUNERVIL
  • RAUNORINE
  • RAUPASIL
  • RAUPOID
  • RAURINE
  • RAUSAN
  • RAUSEDIL
  • RAUSEDYL
  • RAUSERPIN
  • RAUSERPINE
  • RAUSERPOL
  • RAUSINGLE
  • RAUTRIN
  • RAUWASEDIN
  • RAUWILID
  • RAUWILOID
  • RAUWIPUR
  • RAUWOLEAF
  • RECIPIN
  • RESALTEX
  • RESEDREX
  • RESEDRIL
  • RESERBAL
  • RESERCAPS
  • RESERCEN
  • RESERFIA
  • RESERLOR
  • RESERP
  • RESERPAMED
  • RESERPENE
  • RESERPEX
  • RESERPIC ACID METHYL ESTER 3,4,5-TRIMETHOXYBENZOATE (ESTER)
  • RESERPIL
  • RESERPIN
  • RESERPINA
  • RESERPINE
  • (-)-RESERPINE
  • RESERPOID
  • RESERPUR
  • RESERUTIN
  • RESIDINE
  • RESINE
  • RESOCALM
  • RESPERIN
  • RESPITAL
  • RESTRAN
  • REZERPIN
  • RISERPA
  • RIVASIN
  • ROXEL
  • ROXINOID
  • SALUPRES
  • SANDRIL
  • SANDRON
  • SEDARAUPIN
  • SEDARAUPINA
  • SEDSERP
  • SEOMINAL
  • SERFIN
  • SERFOLIA
  • SEROLFIA
  • SERP-AFD
  • SERPALAN
  • SERPALOID
  • SERPANRAY
  • SERPASIL
  • SERPASIL PREMIX
  • SERPASOL
  • SERPATE
  • SERPAZOL
  • SERPEN
  • SERPENA
  • SERPENTIL
  • SERPENTINA
  • SERPICON
  • SERPILOID
  • SERPILUM
  • SERPINE
  • SERPINE (PHARMACEUTICAL)
  • SERPIPUR
  • SERPIVITE
  • SERPOGEN
  • SERPOID
  • SERPONE
  • SERTABS
  • SERTENS
  • SERTINA
  • SK-RESERPINE
  • SOLFO SERPINE
  • SUPERGAN
  • T-SERP
  • TEMPO-RESERPINA
  • TEMPOSERPINE
  • TENSANYL
  • TENSIONAL
  • TENSIONORME
  • TERBOLAN
  • TRANSERPIN
  • 3,4,5-TRIMETHOXYBENZOYL METHYL RESERPATE
  • TRISERPIN
  • TYLANDRIL
  • UNILORD
  • UNITENSEN
  • USAF CB-27
  • V-SERP
  • VERILOID
  • VIO-SERPINE
  • VIXO
  • YOHIMBAN-16-CARBOXYLIC ACID DERIVATIVE OF BENZ(G)INDOLO(2,3-A)QUINOLIZINE

Version 2.7.1 rev 3