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TRYPAN BLUE

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The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 72-57-1
none
DOT Hazard Label USCG CHRIS Code
data unavailable none
NIOSH Pocket Guide International Chem Safety Card
none none
NFPA 704
data unavailable
General Description
PHYSICAL DESCRIPTION: Bluish-gray to dark blue powder. (NTP, 1992)

The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
  • Explosive
Air & Water Reactions
Azo dyes can be explosive when suspended in air at specific concentrations. Slightly soluble in water.
Fire Hazard
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health Hazard
ACUTE/CHRONIC HAZARDS: This chemical may cause irritation and may be absorbed through the skin. It is a positive animal carcinogen. When heated to decomposition this compound emits very toxic fumes of nitrogen oxides, sulfur oxides, carbon monoxide and carbon dioxide. (NTP, 1992)
Reactivity Profile
TRYPAN BLUE is an azo compound. Azo, diazo, azido compounds can detonate. This applies in particular to organic azides that have been sensitized by the addition of metal salts or strong acids. Toxic gases are formed by mixing materials of this class with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. Flammable gases are formed by mixing materials in this group with alkali metals. Explosive combination can occur with strong oxidizing agents, metal salts, peroxides, and sulfides. This chemical is incompatible with strong oxidizing agents and strong acids. (NTP, 1992)
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
No information available.
Firefighting
Fires involving this compound may be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Non-Fire Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should store this material under ambient temperatures. (NTP, 1992)
Protective Clothing
MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds The information in CAMEO Chemicals comes from a variety of data sources.
Chemical Formula:
  • C34H28N6O14S4.4Na
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: greater than 572°F (NTP, 1992)
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity: data unavailable
Boiling Point: data unavailable
Molecular Weight: 964.88 (NTP, 1992)
Water Solubility: 1 to 10 mg/mL at 68°F (NTP, 1992)
Ionization Energy/Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

No PAC information available.

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Cybersecurity and Infrastructure Security Agency's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
EPCRA 302
EHS TPQ
EPCRA 304
EHS RQ
CERCLA RQ EPCRA 313
TRI
RCRA
Code
CAA 112(r)
RMP TQ
Trypan blue 72-57-1 10 pounds 313 U236

(EPA List of Lists, 2022)

CISA Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • AMANIL SKY BLUE
  • AMANIL SKY BLUE R
  • AMIDINE BLUE 4B
  • AZIDIN BLAU 3B
  • AZINDINE BLUE 3B
  • AZURRO DIRETTO 3B
  • BENCIDAL BLUE 3B
  • BENZAMINBLAU 3B
  • BENZAMINE BLUE
  • BENZAMINE BLUE 3B
  • BENZANIL BLUE 3BN
  • BENZANIL BLUE R
  • BENZO BLUE
  • BENZO BLUE 3B
  • BENZO BLUE 3BS
  • BENZOBLAU 3B
  • BLEU DIAMINE
  • BLEU DIAZOLE N 3B
  • BLEU DIRECTE 3B
  • BLEU TRYPANE N
  • BLEUE DIRETTO 3B
  • BLUE 3B
  • BLUE EMB
  • BRASILAMINA BLUE 3B
  • C.I. 23850
  • C.I. DIRECT BLUE 14
  • C.I. DIRECT BLUE 14, TETRASODIUM SALT
  • CHLORAMINE BLUE
  • CHLORAMINE BLUE 3B
  • CHROME LEATHER BLUE 3B
  • CONGO BLUE
  • CONGO BLUE 3B
  • CRESOTINE BLUE 3B
  • DIAMINE BLUE
  • DIAMINE BLUE 3B
  • DIAMINEBLUE
  • DIAPHTAMINE BLUE TH
  • DIAZINE BLUE 3B
  • DIAZOL BLUE 3B
  • 3,3'-((3,3'-DIMETHYL-4,4'-BIPHENYLYLENE)BIS(AZO))BIS(5-AMINO-4-HYDROXY-2,7-NAPHTHALENEDISULFONIC ACID TETRASODIUM SALT
  • DIPHENYL BLUE
  • DIPHENYL BLUE 3B
  • DIRECT BLUE 14
  • DIRECT BLUE 3B
  • DIRECT BLUE M 3B
  • HISPAMIN BLUE 3BX
  • NAPHTHAMINE BLUE 3BX
  • NAPHTHYLAMINE BLUE
  • NCI C61289
  • NIAGARA BLUE
  • NIAGARA BLUE 3B
  • ORION BLUE 3B
  • PARAMINE BLUE 3B
  • PONTAMINE BLUE 3BX
  • SODIUM DITOLYLDISAZOBIS-8-AMINO-1-NAPHTHOL-3,6-DISULFONATE
  • SODIUM DITOLYLDISAZOBIS-8-AMINO-1-NAPHTHOL-3,6-DISULPHONATE
  • TB
  • TRIPAN BLUE
  • TRYPAN (CONGO) BLUE
  • TRYPAN BLUE
  • TRYPAN BLUE BPC
  • TRYPAN BLUE SODIUM SALT
  • TRYPANE BLUE

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