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NICOTINIC ACID

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The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 59-67-6
none
DOT Hazard Label USCG CHRIS Code
data unavailable none
NIOSH Pocket Guide International Chem Safety Card
none
NFPA 704
data unavailable
General Description
PHYSICAL DESCRIPTION: Odorless white crystalline powder with a feebly acid taste. pH (saturated aqueous solution) 2.7. pH (1.3% solution) 3-3.5. (NTP, 1992)

The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
none
Air & Water Reactions
Water soluble.
Fire Hazard
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health Hazard
SYMPTOMS: Symptoms of exposure to this compound include impaired liver function, dryness of the skin, anorexia, nausea, vomiting, diarrhea, activation of peptic ulcers, hepatic disease, hyperuricemia and circulatory collapse (after rapid intravenous injection). It may cause temporary flushing and a feeling of warmth, temporary headache, itching, tingling, skin rash and allergies. It may also cause burning of the skin, face and upper trunk and elevation of serum bilirubin. Other symptoms include mild irritation of upper respiratory tract and gastrointestinal disturbances. It may cause dyspepsia, hyperpigmentation, decrease in excretion of bromosulfophthalein, increase of plasma transaminase activities, incidence of acute gouty arthritis, acanthosis nigricans, hyperglycemia, increased vasodilation and cystoid edema of the macula. It may also cause furunculosis and other skin lesions, hypotension, abdominal cramps, mild diabetes and urticaria. Other symptoms include pruritus, toxic amblyopia, jaundice and decreased glucose tolerance.

ACUTE/CHRONIC HAZARDS: This compound may cause mild irritation to the upper respiratory tract. When heated to decomposition it may emit toxic fumes of NOx. (NTP, 1992)
Reactivity Profile
NICOTINIC ACID is incompatible with strong oxidizers. It is also incompatible with sodium nitrite. (NTP, 1992)
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

Use caution: Liquids with this reactive group classification have been known to react with the absorbent listed below. More info about absorbents, including situations to watch out for...

  • Mineral-Based & Clay-Based Absorbents

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
No information available.
Firefighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)
Non-Fire Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should store this material under ambient temperatures. (NTP, 1992)
Protective Clothing
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds The information in CAMEO Chemicals comes from a variety of data sources.

Note: For Vapor Density and Specific Gravity, comparing the value to 1.0 can tell you if the chemical will likely sink/rise in air or sink/float in fresh water (respectively). Short phrases have been added to those values below as an aid. However, make sure to also consider the circumstances of a release. The Vapor Density comparisons are only valid when the gas escaping is at the same temperature as the surrounding air itself. If the chemical is escaping from a container where it was pressurized or refrigerated, it may first escape and behave as a heavy gas and sink in the air (even if it has a Vapor Density value less than 1). Also, the Specific Gravity comparisons are for fresh water (density 1.0 g/mL). If your spill is in salt water (density about 1.027 g/mL), you need to adjust the point of comparison. There are some chemicals that will sink in fresh water and float in salt water.
Chemical Formula:
  • C6H5NO2
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: 457°F (NTP, 1992)
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity: 1.473 (NTP, 1992) - Denser than water; will sink
Boiling Point: Sublimes (NTP, 1992)
Molecular Weight: 123.11 (NTP, 1992)
Water Solubility: 10 to 50 mg/mL at 63°F (NTP, 1992)
Ionization Energy/Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

No PAC information available.

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Cybersecurity and Infrastructure Security Agency's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

No regulatory information available.

CISA Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • ACIDIUM NICOTINICUM
  • AKOTIN
  • ANTI-PELLAGRA VITAMIN
  • APELAGRIN
  • BETA-PYRIDINECARBOXYLIC ACID
  • BIONIC
  • 3-CARBOXYLPYRIDINE
  • 3-CARBOXYPYRIDINE
  • DASKIL
  • DAVITAMON PP
  • DIREKTAN
  • EFACIN
  • LINIC
  • NAH
  • NAOTIN
  • NIACIN
  • NIASPAN
  • NICACID
  • NICAMIN
  • NICANGIN
  • NICO
  • NICO-400
  • NICO-SPAN
  • NICOBID
  • NICOCAP
  • NICOCIDIN
  • NICOCRISINA
  • NICODAN
  • NICODELMINE
  • NICOLAR
  • NICONACID
  • NICONAT
  • NICONAZID
  • NICOROL
  • NICOSAN 3
  • NICOSIDE
  • NICOSYL
  • NICOTAMIN
  • NICOTENE
  • NICOTIL
  • NICOTINE ACID
  • NICOTINIC ACID
  • NICOTINIPCA
  • NICOTINOYLHYDRAZINE
  • NICOVASAN
  • NICOVASEN
  • NICOVEL
  • NICYL
  • NIPELLEN
  • NYCLIN
  • P.P. FACTOR-PELLAGRA PREVENTIVE FACTOR
  • PELLAGRA PREVENTIVE FACTOR
  • PELLAGRAMIN
  • PELLAGRIN
  • PELONIN
  • PEVITON
  • PP FACTOR
  • PYRIDINE-3-CARBONIC ACID
  • PYRIDINE-3-CARBOXYLIC ACID
  • PYRIDINE-BETA-CARBOXYLIC ACID
  • 3-PYRIDINECARBOXYLIC ACID
  • 3-PYRIDYLCARBOXYLIC ACID
  • S115
  • SK-NIACIN
  • SR 4390
  • TINIC
  • VITAPLEX N
  • WAMPOCAP

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