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NITROFURANTOIN

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The Chemical Identifier fields include common identification numbers, the NFPA diamond, U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 67-20-9
none
DOT Hazard Label USCG CHRIS Code
data unavailable none
NIOSH Pocket Guide International Chem Safety Card
none none
NFPA 704
data unavailable
General Description
PHYSICAL DESCRIPTION: Odorless lemon yellow crystals or fine yellow powder. Bitter taste. (NTP, 1992)

The Hazard fields include special hazard alerts, air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
none
Air & Water Reactions
Insoluble in water.
Fire Hazard
Flash point data for this chemical are not available; however, it is probably combustible. (NTP, 1992)
Health Hazard
SYMPTOMS: Symptoms of exposure to this compound may include fever, nausea, vomiting, diarrhea, chills, cough, dyspnea, chest pain, pulmonary infiltration, hepatitis, eosinophilia, interstitial pneumonitis or fibrosis, hemolytic anemia, megaloblastic anemia, cholestatic jaundice, granulocytopenia, leukopenia and headache. Other symptoms may include anorexia, malaise, abdominal pain, acute, subacute and chronic pulmonary reactions, insidious onset of pulmonary reactions, consolidation or pleural effusion on x-ray, altered pulmonary function, exfoliative dermatitis, multiforme, maculopapular, erythematous or eczematous eruption, pruritus, urticaria, anaphylaxis, angioedema, asthmatic attack in persons with a history of asthma, arthralgia, pancreatitis, sialadenitis, agranulocytosis, thrombocytopenia and dizziness. It can cause various neurological disorders, vertigo, drowsiness, nystagmus, muscular aches, hypersensitivity reactions and hepatocellular damage. Severe polyneuropathies with demyelination and degeneration of both sensory and motor nerves have been reported. Signs of denervation and muscular atrophy result. Other symptoms may include bleeding, acute polyneuritis, cerebellar dysfunction and circulatory collapse. It can cause ataxic gait. Eye contact may result in severe itching and burning of the eyes with excessive tearing, retrobulbar neuritis and vertical diplopia. Large doses have decreased spermatogenesis through direct action on the seminiferous tubules. Other symptoms include ataxia and changes in urine composition.

ACUTE/CHRONIC HAZARDS: This compound is harmful if swallowed or inhaled. It may cause irritation. When heated to decomposition it emits toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides. (NTP, 1992)
Reactivity Profile
NITROFURANTOIN is sensitive to light. This chemical is incompatible with alkalis. It is also incompatible with strong oxidizers and strong acids. It decomposes on contact with metals other than stainless steel and aluminum. (NTP, 1992)
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

Use caution: Liquids with this reactive group classification have been known to react with the absorbents listed below. More info about absorbents, including situations to watch out for...

  • Cellulose-Based Absorbents
  • Expanded Polymeric Absorbents

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
No information available.
Firefighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)
Non-Fire Response
SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

STORAGE PRECAUTIONS: You should protect this material from exposure to light, and store it in a freezer. (NTP, 1992)
Protective Clothing
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.

INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing.

INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.

OTHER: Since this chemical is a known or suspected carcinogen you should contact a physician for advice regarding the possible long term health effects and potential recommendation for medical monitoring. Recommendations from the physician will depend upon the specific compound, its chemical, physical and toxicity properties, the exposure level, length of exposure, and the route of exposure. (NTP, 1992)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds. The information in CAMEO Chemicals comes from a variety of data sources.
Chemical Formula:
  • C8H6N4O5
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: 514 ° F (decomposes) (NTP, 1992)
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity: data unavailable
Boiling Point: data unavailable
Molecular Weight: 238.16 (NTP, 1992)
Water Solubility: less than 0.1 mg/mL at 66┬░ F (NTP, 1992)
Ionization Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

No PAC information available.

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Department of Homeland Security's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

No regulatory information available.

DHS Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • BENKFURAN
  • BERKFURIN
  • CHEMIOFURAN
  • CYANTIN
  • CYSTIT
  • DANTAFUR
  • FUA-MED
  • FUR-REN
  • FURACHEL
  • FURADANTIN
  • FURADANTINE
  • FURADANTOIN
  • FURADOINE
  • FURADONIN
  • FURADONINE
  • FURADONTIN
  • FURALAN
  • FURANTOIN
  • FURATOIN
  • FURINA
  • FUROBACTINA
  • FUROPHEN
  • HYDANTOIN, 1-((5-NITROFURFURYLIDENE)AMINO)-
  • HYDANTOIN, 1-[(5-NITROFURFURYLIDENE)AMINO]-
  • 2,4-IMIDAZOLIDINEDIONE, 1-(((5-NITRO-2-FURANYL)METHYLENE)AMINO)-
  • ITURAN
  • MACRODANTIN
  • N-(5-NITRO-2-FURFURYLIDENE)-1-AMINOHYDANTOIN
  • N-(5-NITROFURFURYLIDENE)-1-AMINOHYDANTOIN
  • N-TOIN
  • NCI-C55196
  • NIFURANTIN
  • NITOIN
  • 1-(((5-NITRO-2-FURANYL)METHYLENE)AMINO)-2,4-IMIDAZOLIDINEDIONE
  • 1-(5-NITRO-2-FURFURYLIDENAMINO)HYDANTOIN
  • 1-(5-NITRO-2-FURFURYLIDENEAMINO)HYDANTOIN
  • NITROFURANTOIN
  • 5-NITROFURANTOIN
  • 1-((5-NITROFURFURYLIDENE)AMINO)HYDANTOIN
  • 1-[(5-NITROFURFURYLIDENE)AMINO]HYDANTOIN
  • NOVOFURAN
  • NSC 2107
  • ORAFURAN
  • PARFURAN
  • TRANTOIN
  • URANTOIN
  • URIZEPT
  • URO-TABLINEU
  • URODIL
  • URODIN
  • UROFURIN
  • UROLONG
  • USAF EA-2
  • WELFURIN
  • ZOOFURIN

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