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ENFLURANE

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The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 13838-16-9
none
DOT Hazard Label USCG CHRIS Code
data unavailable none
NIOSH Pocket Guide International Chem Safety Card
Enfluraneexternal link
NFPA 704
data unavailable
General Description
Enflurane (Ethrane, 2-chloro-1,1,2-trifluoroethyldifluoromethyl ether) is a nonflammable halogenated hydrocarbon that exists as a clear, colorless, odorless to sweet, volatile liquid at ordinary temperature and pressure. Bp: 56.8°C. Density 1.50 g cm-3 at room temperature. Used as an anesthetic.

The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
none
Air & Water Reactions
No rapid reaction with air. No rapid reaction with water.
Fire Hazard
No information available.
Health Hazard
Excerpt from NIOSH Pocket Guide for Enfluraneexternal link:

Exposure Routes: Inhalation, ingestion, skin and/or eye contact

Symptoms: Irritation eyes; central nervous system depression, analgesia, anesthesia, convulsions, resp depression

Target Organs: Eyes, central nervous system (NIOSH, 2022)
Reactivity Profile
The material ENFLURANE is incompatible with the following oxidizing materials, peroxides, combustible materials. Although nonflammable, a fire may cause enflurane to decompose to toxic compounds including phosgene, hydrogen chloride, and hydrogen fluoride. Decomposes slowly in the light.
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
No information available.
Firefighting
No information available.
Non-Fire Response
No information available.
Protective Clothing
Excerpt from NIOSH Pocket Guide for Enfluraneexternal link:

Skin: No recommendation is made specifying the need for personal protective equipment for the body.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin: No recommendation is made specifying the need for washing the substance from the skin (either immediately or at the end of the work shift).

Remove: No recommendation is made specifying the need for removing clothing that becomes wet or contaminated.

Change: No recommendation is made specifying the need for the worker to change clothing after the workshift. (NIOSH, 2022)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Excerpt from NIOSH Pocket Guide for Enfluraneexternal link:

Eye: IRRIGATE IMMEDIATELY - If this chemical contacts the eyes, immediately wash (irrigate) the eyes with large amounts of water, occasionally lifting the lower and upper lids. Get medical attention immediately.

Skin: SOAP WASH - If this chemical contacts the skin, wash the contaminated skin with soap and water.

Breathing: RESPIRATORY SUPPORT - If a person breathes large amounts of this chemical, move the exposed person to fresh air at once. If breathing has stopped, perform artificial respiration. Keep the affected person warm and at rest. Get medical attention as soon as possible.

Swallow: MEDICAL ATTENTION IMMEDIATELY - If this chemical has been swallowed, get medical attention immediately. (NIOSH, 2022)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds The information in CAMEO Chemicals comes from a variety of data sources.
Chemical Formula:
  • CHF2OCF2CHClF
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: data unavailable
Vapor Pressure: 175 mmHg (NIOSH, 2022)
Vapor Density (Relative to Air): data unavailable
Specific Gravity: 1.52 at 77°F (NIOSH, 2022)
Boiling Point: 134°F at 760 mmHg (NIOSH, 2022)
Molecular Weight: 184.5 (NIOSH, 2022)
Water Solubility: Low (NIOSH, 2022)
Ionization Energy/Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

No PAC information available.

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Cybersecurity and Infrastructure Security Agency's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

No regulatory information available.

CISA Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • 347
  • ALYRANE
  • ANESTHETIC COMPOUND NO. 347
  • 2-CHLORO-1,1,2-TRIFLUORO-1-DIFLUOROMETHOXYETHANE
  • 2-CHLORO-1,1,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER
  • 2-CHLORO-1-(DIFLUOROMETHOXY)-1,1,2-TRIFLUOROETHANE
  • COMPOUND 347
  • EFRANE
  • ENFLURANE
  • (+-)-ENFLURANE
  • ETHER, 2-CHLORO-1,1,2-TRIFLUOROETHYL DIFLUOROMETHYL
  • ETHRANE
  • ETHRANE®
  • METHYLFLURETHER
  • NSC 115944
  • OHIO 347
  • R-E 235CA2

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