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DICHLORODIMETHYL ETHER, SYMMETRICAL

6.1 - Poison 3 - Flammable liquid
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The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 542-88-1   (DICHLORODIMETHYL ETHER)
DOT Hazard Label USCG CHRIS Code
  • Poison
  • Flammable Liquid
none
NIOSH Pocket Guide International Chem Safety Card
bis-Chloromethyl etherexternal link
NFPA 704
Diamond Hazard Value Description
3
4 1
Blue Health 4 Can be lethal.
Red Flammability 3 Can be ignited under almost all ambient temperature conditions.
Yellow Instability 1 Normally stable but can become unstable at elevated temperatures and pressures.
White Special
(NFPA, 2010)
General Description
A colorless volatile liquid with a chloroform-like odor. Toxic by inhalation, skin absorption and ingestion. Dangerous fire risk - flash point below 0°F. Vapors much denser than air. Insoluble in water and denser than water. Used to make paints and varnish, and as a solvent.

The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
  • Highly Flammable
  • Water-Reactive
Air & Water Reactions
Highly flammable. Insoluble in water. Reacts with water to form hydrochloric acid & formaldehyde.
Fire Hazard
Container may explode in heat of fire. When heated to decomposition, it emits very toxic fumes of chlorides. Decomposed by water to hydrochloric acid and formaldehyde. Avoid water: hydrolyzes very rapidly (half life 10-40 seconds) on contact with water. Avoid decomposing heat, powerful oxidizers, areas of high fire hazard and moist air. (EPA, 1998)
Health Hazard
Acute toxicity is high by ingestion, inhalation, and skin irritation. Small quantities may cause death or permanent injury after very short exposure. Chloromethyl ether is an alkylating agent which is a recognized human carcinogen. There is a strong association between industrial exposure and excess lung cancer. (EPA, 1998)
Reactivity Profile
DICHLORODIMETHYL ETHER is incompatible with the following: Acids, water [Note: Reacts with water to form hydrochloric acid & formaldehyde.] (NIOSH, 2016).
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:

As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions.

SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Firefighting
Move container from fire area if you can do so without risk. Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material.

Small fires: dry chemical, carbon dioxide, water spray, or foam. Large fires: water spray, fog, or foam. (EPA, 1998)
Non-Fire Response
Excerpt from ERG Guide 131 [Flammable Liquids - Toxic]:

Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire. ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. A vapor-suppressing foam may be used to reduce vapors.

SMALL SPILL: Absorb with earth, sand or other non-combustible material and transfer to containers for later disposal. Use clean, non-sparking tools to collect absorbed material.

LARGE SPILL: Dike far ahead of liquid spill for later disposal. Water spray may reduce vapor, but may not prevent ignition in closed spaces. (ERG, 2016)
Protective Clothing
Skin: Wear appropriate personal protective clothing to prevent skin contact.

Eyes: Wear appropriate eye protection to prevent eye contact.

Wash skin: The worker should immediately wash the skin when it becomes contaminated. The worker should wash daily at the end of each work shift.

Remove: Work clothing that becomes wet should be immediately removed due to its flammability hazard(i.e. for liquids with flash point < 100°F)

Change: Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premise.

Provide: Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substance; this is irrespective of the recommendation involving the wearing of eye protection. Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] (NIOSH, 2016)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Note: Chloromethyl ether is a recognized human carcinogen.

Signs and Symptoms of Chloromethyl Ether Exposure: Acute exposure to chloromethyl ether may produce the following signs and symptoms: severe irritation and burning of the skin, eyes, and mucous membranes. Sore throat, fever, chills, dypsnea (difficulty breathing), chronic bronchitis, and pulmonary edema with productive cough may be noted.

Emergency Life-Support Procedures: Acute exposure to chloromethyl ether may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to chloromethyl ether.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to chloromethyl ether.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
3. Remove and isolate contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas thoroughly with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support.
2. DO NOT induce vomiting or attempt to neutralize!
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility. (EPA, 1998)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds The information in CAMEO Chemicals comes from a variety of data sources.
Chemical Formula:
  • C2H4Cl2O
Flash Point: Less than 66.2F (EPA, 1998)
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: -42.7 ° F (EPA, 1998)
Vapor Pressure: 30 mm Hg at 71.6 ° F (EPA, 1998)
Vapor Density (Relative to Air): 4 (EPA, 1998)
Specific Gravity: 1.315 at 68 ° F (EPA, 1998)
Boiling Point: 223 ° F at 760 mm Hg (EPA, 1998)
Molecular Weight: 114.97 (EPA, 1998)
Water Solubility: Reacts with water (NIOSH, 2016)
Ionization Potential: data unavailable
IDLH: A potential occupational carcinogen. (NIOSH, 2016)

AEGLs (Acute Exposure Guideline Levels)

Final AEGLs for Bis (chloromethyl) ether (542-88-1)
Exposure Period AEGL-1 AEGL-2 AEGL-3
10 minutes NR 0.055 ppm 0.23 ppm
30 minutes NR 0.055 ppm 0.23 ppm
60 minutes NR 0.044 ppm 0.18 ppm
4 hours NR 0.028 ppm 0.11 ppm
8 hours NR 0.02 ppm 0.075 ppm
NR = Not recommended due to insufficient data.
(NAC/NRC, 2017)

ERPGs (Emergency Response Planning Guidelines)

Chemical ERPG-1 ERPG-2 ERPG-3
Bis (Chloromethyl) Ether (542-88-1) ID 0.1 ppm 0.5 ppm
ID = insufficient data.
(AIHA, 2016)

PACs (Protective Action Criteria)

Chemical PAC-1 PAC-2 PAC-3
Dichloromethyl ether; (bis(Chloromethyl)ether) (542-88-1) 0.004 ppm 0.044 ppm 0.18 ppm
(DOE, 2016)

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Department of Homeland Security's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
EPCRA 302
EHS TPQ
EPCRA 304
EHS RQ
CERCLA RQ EPCRA 313
TRI
RCRA
Code
CAA 112(r)
RMP TQ
Bis(chloromethyl) ether 542-88-1 100 pounds 10 pounds 10 pounds 313 P016 1000 pounds
Chloromethyl ether 542-88-1 100 pounds 10 pounds 10 pounds X P016 1000 pounds
Dichloromethyl ether 542-88-1 100 pounds 10 pounds 10 pounds X P016 1000 pounds
Methane, oxybis[chloro- 542-88-1 100 pounds 10 pounds 10 pounds X P016 1000 pounds

(EPA List of Lists, 2015)

DHS Chemical Facility Anti-Terrorism Standards (CFATS)

RELEASE THEFT SABOTAGE
Chemical of Interest CAS Number Min Conc STQ Security
Issue
Min Conc STQ Security
Issue
Min Conc STQ Security
Issue
Chloromethyl ether; [Methane, oxybis(chloro-)] 542-88-1 1.00 % 1000 pounds toxic

(DHS, 2007)

OSHA Process Safety Management (PSM) Standard List

Chemical Name CAS Number Threshold Quantity (TQ)
Bis(Chloromethyl) Ether 542-88-1 100 pounds

(OSHA, 2011)

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • ALPHA,ALPHA'-DICHLORODIMETHYL ETHER
  • BCME
  • BIS(CHLOROMETHYL) ETHER
  • BIS-CHLOROMETHYL ETHER
  • BIS-CME
  • CHLORO(CHLOROMETHOXY) METHANE
  • CHLOROMETHYL ETHER
  • DICHLORINATED METHYL OXIDE
  • DICHLORODIMETHYL ETHER
  • DICHLORODIMETHYL ETHER, SYMMETRICAL
  • 1,1'-DICHLORODIMETHYL ETHER
  • DICHLOROMETHYL ETHER
  • DIMETHYL-1,1'-DICHLOROETHER
  • ETHER, BIS(CHLOROMETHYL)
  • METHANE, OXYBIS(CHLORO-
  • METHANE, OXYBIS[CHLORO-
  • MONOCHLOROMETHYL ETHER
  • OXYBIS(CHLOROMETHANE)
  • OXYBIS[CHLOROMETHANE]
  • SYM-DICHLORO-DIMETHYL ETHER
  • SYM-DICHLOROMETHYL ETHER

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