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DISULFOTON

6.1 - Poison
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The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 298-04-4
DOT Hazard Label USCG CHRIS Code
  • Poison
NIOSH Pocket Guide International Chem Safety Card
Disulfotonexternal_link
NFPA 704
data unavailable
General Description
Disulfoton is a dark, yellow, oily liquid with a characteristic sulfur odor. It is a water emulsifiable liquid. It is toxic by inhalation, skin absorption, and/or ingestion. Exposure to skin or eyes may cause burns. It is combustible but does not ignite easily. When exposed to high temperature this material may emit toxic fumes. It is used as a pesticide. May be found in the form of a dry mixture where the liquid is absorbed onto a dry carrier.

The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
none
Air & Water Reactions
Slightly soluble in water.
Fire Hazard
Material may burn but does not ignite easily. Cylinder may explode in the heat of fire. Poisonous gases may be generated from the fire or runoff water. Oxidizable in air. (EPA, 1998)
Health Hazard
It is classified as super toxic. Probable oral lethal dose in humans is less than 5 mg/kg or a taste (less than 7 drops) for a 70 kg (150 lb.) person. It is poisonous and may be fatal if inhaled, swallowed, or absorbed through the skin. Contact may cause burns to skin and eyes. (EPA, 1998)
Reactivity Profile
DISULFOTON is incompatible with the following: Alkalis (NIOSH, 2024). Organothiophosphates, such as DISULFOTON, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
Excerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail tank car or highway tank is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2024)
Firefighting
Fight fire from maximum distance. Dike fire control water for later disposal; do not scatter the material. Wear positive pressure breathing apparatus and special protective clothing.

Extinguish with dry chemical, carbon dioxide, water spray, fog, or foam. (EPA, 1998)
Non-Fire Response
Excerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Prevent entry into waterways, sewers, basements or confined areas. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS. (ERG, 2024)
Protective Clothing
Excerpt from NIOSH Pocket Guide for Disulfotonexternal link:

Skin: PREVENT SKIN CONTACT - Wear appropriate personal protective clothing to prevent skin contact.

Eyes: PREVENT EYE CONTACT - Wear appropriate eye protection to prevent eye contact.

Wash skin: WHEN CONTAMINATED - The worker should immediately wash the skin when it becomes contaminated.

Remove: WHEN WET OR CONTAMINATED - Work clothing that becomes wet or significantly contaminated should be removed and replaced.

Change: DAILY - Workers whose clothing may have become contaminated should change into uncontaminated clothing before leaving the work premises.

Provide:
• EYEWASH - Eyewash fountains should be provided in areas where there is any possibility that workers could be exposed to the substances; this is irrespective of the recommendation involving the wearing of eye protection.
• QUICK DRENCH - Facilities for quickly drenching the body should be provided within the immediate work area for emergency use where there is a possibility of exposure. [Note: It is intended that these facilities provide a sufficient quantity or flow of water to quickly remove the substance from any body areas likely to be exposed. The actual determination of what constitutes an adequate quick drench facility depends on the specific circumstances. In certain instances, a deluge shower should be readily available, whereas in others, the availability of water from a sink or hose could be considered adequate.] (NIOSH, 2024)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Note: Disulfoton is a cholinesterase inhibitor.

Signs and Symptoms of Acute Disulfoton Exposure: Acute exposure to disulfoton may produce the following signs and symptoms: pinpoint pupils, blurred vision, headache, dizziness, muscle spasms, and profound weakness. Vomiting, diarrhea, abdominal pain, seizures, and coma may also occur. The heart rate may decrease following oral exposure or increase following dermal exposure. Hypotension (low blood pressure) and chest pain may be noted. Hypertension (high blood pressure) is not uncommon. Respiratory symptoms include dyspnea (shortness of breath), respiratory depression, and respiratory paralysis. Psychosis may occur.

Emergency Life-Support Procedures: Acute exposure to disulfoton may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to disulfoton.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self- exposure to disulfoton.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of disulfoton is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
4.Ipecac should not be administered to children under 6 months of age.Warning: Ingestion of disulfoton may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step
4.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility. (EPA, 1998)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds The information in CAMEO Chemicals comes from a variety of data sources.

Note: For Vapor Density and Specific Gravity, comparing the value to 1.0 can tell you if the chemical will likely sink/rise in air or sink/float in fresh water (respectively). Short phrases have been added to those values below as an aid. However, make sure to also consider the circumstances of a release. The Vapor Density comparisons are only valid when the gas escaping is at the same temperature as the surrounding air itself. If the chemical is escaping from a container where it was pressurized or refrigerated, it may first escape and behave as a heavy gas and sink in the air (even if it has a Vapor Density value less than 1). Also, the Specific Gravity comparisons are for fresh water (density 1.0 g/mL). If your spill is in salt water (density about 1.027 g/mL), you need to adjust the point of comparison. There are some chemicals that will sink in fresh water and float in salt water.
Chemical Formula:
  • C8H19O2PS3
Flash Point: greater than 180°F (NIOSH, 2024)
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: Greater than -13°F (EPA, 1998)
Vapor Pressure: 0.00018 mmHg at 68°F (EPA, 1998)
Vapor Density (Relative to Air): data unavailable
Specific Gravity: 1.144 (EPA, 1998) - Denser than water; will sink
Boiling Point: 270 to 271°F at 1.5 mmHg (EPA, 1998)
Molecular Weight: 274.38 (EPA, 1998)
Water Solubility: 0.003 % at 73°F (NIOSH, 2024)
Ionization Energy/Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

Chemical PAC-1 PAC-2 PAC-3
Disulfoton (298-04-4) 0.18 mg/m3 2 mg/m3 8.8 mg/m3
(DOE, 2024)

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Cybersecurity and Infrastructure Security Agency's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
EPCRA 302
EHS TPQ
EPCRA 304
EHS RQ
CERCLA RQ EPCRA 313
TRI
RCRA
Code
CAA 112(r)
RMP TQ
Disulfoton 298-04-4 500 pounds 1 pound 1 pound P039

(EPA List of Lists, 2024)

CISA Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • BAY 19639
  • BAYER 19639
  • DI-SYSTON
  • DI-SYSTON G
  • DI-SYSTON®
  • DIMAZ
  • DISULFATON
  • DISULFOTON
  • DISYSTOX
  • DITHIODEMETON
  • DITHIOSYSTOX
  • DUTION
  • EKATIN TD
  • ENT 23,437
  • ENT-23437
  • ETHYL THIOMETON
  • ETHYLTHIOMETON B
  • FRUMIN
  • FRUMIN AL
  • FRUMIN G
  • GLEBOFOS
  • M 74
  • M 74 (PESTICIDE)
  • M 74(PESTICIDE)
  • M-74
  • O,O-DIETHYL 2-ETHYLTHIOETHYL PHOSPHORODITHIOATE
  • O,O-DIETHYL S-(2-(ETHYLTHIO)ETHYL) PHOSPHORODITHIOATE
  • O,O-DIETHYL S-(2-ETHTHIOETHYL) PHOSPHORODITHIOATE
  • O,O-DIETHYL S-(2-ETHTHIOETHYL)THIOTHIONOPHOSPHATE
  • O,O-DIETHYL S-(2-ETHYLMERCAPTOETHYL) DITHIOPHOSPHATE
  • O,O-DIETHYL S-2-(ETHYLTHIO)-ETHYL PHOSPHORODITHIOATE
  • O,O-DIETHYL S-2-(ETHYLTHIO)ETHYL PHOSPHORODITHIOATE
  • O,O-DIETHYL S-[2-(ETHYLTHIO)ETHYL] DITHIOPHOSPHATE
  • O,O-DIETHYL S-[2-(ETHYLTHIO)ETHYL] PHOSPHORODITHIOATE
  • O,O-DIETHYL-5-2-(ETHYLTHIO)ETHYL PHOSPHODITHIOATE
  • O,O-ETHYL S-2(ETHYLTHIO)ETHYL PHOSPHORODITHIOATE
  • PHOSPHORODITHIOIC ACID, O,O-DIETHYL S-(2-(ETHYLTHIO)ETHYL) ESTER
  • PHOSPHORODITHIONIC ACID, S-2-(ETHYLTHIO)ETHYL O,O-DIETHYL ESTER
  • S 276
  • S-2-(ETHYLTHIO)ETHYL O,O-DIETHYL ESTER OF PHOSPHORODITHIOIC ACID
  • SOLVIREX
  • THIODEMETON
  • THIODEMETRON
  • VUAGT 1-4
  • VUAGT 1964

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