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AMPHETAMINE

6.1 - Poison
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The Chemical Identifier fields include common identification numbers, the NFPA diamond, U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 300-62-9   (AMPHETAMINE)
DOT Hazard Label USCG CHRIS Code
  • Poison
none
NIOSH Pocket Guide International Chem Safety Card
none none
NFPA 704
Diamond Hazard Value Description
1
3 0
Blue Health 3 Can cause serious or permanent injury.
Red Flammability 1 Must be preheated before ignition can occur.
Yellow Instability 0 Normally stable, even under fire conditions.
White Special
(NFPA, 2010)
General Description
Colored liquid with an amine odor. Used as a pharmaceutical, a central nervous system stimulant. (EPA, 1998)

The Hazard fields include special hazard alerts, air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
none
Air & Water Reactions
No rapid reaction with air. No rapid reaction with water.
Fire Hazard
Dangerous when exposed to heat or flames. Upon decomposition, nitrogen oxides are emitted. Can react with oxidizing materials. (EPA, 1998)
Health Hazard
It is classified as extremely hazardous. Probable lethal dose in humans is 5-50 mg/kg or 7 drops to 1 teaspoon for a 70 kg (150 lb.) person. Habit forming drug which affects the central nervous system. Excessive use may lead to tolerance and physical dependence. Death is possible. (EPA, 1998)
Reactivity Profile
Amines, such as AMPHETAMINE, are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

Use caution: Liquids with this reactive group classification have been known to react with the absorbent listed below. More info about absorbents, including situations to watch out for...

  • Mineral-Based & Clay-Based Absorbents

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Firefighting
Extinguish with carbon dioxide or dry chemical. (EPA, 1998)
Non-Fire Response
(Non-Specific -- Drugs, n.o.s.) Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Shut off ignition sources; no flares, smoking or flames in hazard area. Keep combustibles (wood, paper, oil, etc.) away from spilled material. Do not touch spilled material.

Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal.

Large spills: dike far ahead of spill for later disposal. (EPA, 1998)
Protective Clothing
For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Signs and Symptoms of Amphetamine Exposure: Signs and symptoms of acute amphetamine exposure include the following: headache, flushing or pallor, dry mouth, metallic taste, loss of appetite, abdominal cramps, nausea, vomiting, diarrhea, difficulty urinating, chills or fever, restlessness, dizziness, tremors, and hyperactive reflexes. Mood and behavioral changes may include irritability, apprehensiveness, talkativeness, and confusion. Convulsions and coma may also occur. Cardiovascular signs include hypertension (high blood pressure) and tachycardia (rapid heart beat). Cardiovascular collapse may occur in cases of extreme intoxication.

Emergency Life-Support Procedures: Acute exposure to amphetamine may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to amphetamine.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to amphetamine.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove and isolate contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas thoroughly with water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of amphetamine is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
4. Ipecac should not be administered to children under 6 months of age. Warning: Ingestion of amphetamine may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should be administered only if victims are alert, have an active gag reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step
4. The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Transport to a health care facility. (EPA, 1998)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds. The information in CAMEO Chemicals comes from a variety of data sources.
Chemical Formula:
  • C9H13N
Flash Point: 80 ° F (EPA, 1998)
Lower Explosive Limit (LEL): It is flammable. (EPA, 1998)
Upper Explosive Limit (UEL): It is flammable. (EPA, 1998)
Autoignition Temperature: data unavailable
Melting Point: data unavailable
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): 4.65 (EPA, 1998)
Specific Gravity: 0.913 at 77 ° F (EPA, 1998)
Boiling Point: 392 to 397 ° F at 760 mm Hg (EPA, 1998)
Molecular Weight: 135.2 (EPA, 1998)
Water Solubility: data unavailable
Ionization Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

No PAC information available.

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Department of Homeland Security's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
EPCRA 302
EHS TPQ
EPCRA 304
EHS RQ
CERCLA RQ EPCRA 313
TRI
RCRA
Code
CAA 112(r)
RMP TQ
Amphetamine 300-62-9 1000 pounds 1000 pounds

(EPA List of Lists, 2015)

DHS Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • ACETEDRON
  • ACTEDRON
  • ADDERALL
  • ADIPAN
  • ALLODENE
  • (+-)-ALPHA-METHYL PHENETHYLAMINE
  • ALPHA-METHYL-BETA-PHENYLETHYLAMINE
  • (+-)-ALPHA-METHYLBENZENE- ETHANAMINE
  • ALPHA-METHYLBENZENEETHANAMINE
  • ALPHA-METHYLPHENETHYLAMINE
  • (.+-.)-ALPHA-METHYLPHENETHYLAMINE
  • (+-)-ALPHA-METHYLPHENYL ETHYLAMINE
  • ALPHA-METHYLPHENYLETHYLAMINE
  • (.+-.)-ALPHA-METHYLPHENYLETHYLAMINE
  • AMFETAMINE
  • 2-AMINO-1-PHENYLPROPANE
  • AMPHETAMINE
  • ANOREXIDE
  • ANOREXINE
  • BENZEBAR
  • BENZEDRINE
  • BENZENEETHANAMINE, ALPHA-METHYL-, (.+-.)-
  • BENZENEETHANAMINE, ALPHA-METHYL-,(+-)
  • BENZOLONE
  • BETA-AMINOPROPYLBENZENE
  • BETA-PHENYLISOPROPYLAMINE
  • (+-)-BETA-PHENYLISOPROPYLAMINE
  • (.+-.)-BETA-PHENYLISOPROPYLAMINE
  • DESOXYNOREPHEDRINE
  • (+-)-DESOXYNOREPHEDRINE
  • (.+-.)-DESOXYNOREPHEDRINE
  • DL-1-PHENYL-2-AMINOPROPANE
  • DL-ALPHA-METHYLPHENETHYLAMINE
  • DL-AMPHETAMINE
  • DL-BENZEDRINE
  • ELASTONON
  • FENOPROMIN
  • FINAM
  • ISOAMYNE
  • ISOMYN
  • MECODRIN
  • 1-METHYL-2-PHENYLETHYLAMINE
  • MYDRIAL
  • NOREPHEDRANE
  • NOREPHEDRINE, DEOXY-
  • NOVYDRINE
  • OBESIN
  • OBESINE
  • OKTEDRIN
  • ORTEDRINE
  • PERCOMON
  • PHENAMINE
  • PHENEDRINE
  • PHENETHYLAMINE, ALPHA-METHYL
  • PHENETHYLAMINE, ALPHA-METHYL-, (.+-.)-
  • (.+-.)-1-PHENYL-2-AMINOPROPANE
  • 1-PHENYL-2-AMINOPROPANE
  • 1-PHENYL-2-PROPYLAMINE
  • 3-PHENYL-2-PROPYLAMINE
  • (PHENYLISOPROPYL)AMINE
  • (.+-.)-PHENYLISOPROPYLAMINE
  • PROFAMINA
  • PROPISAMINE
  • PSYCHEDRINE
  • RACEMIC AMPHETAMINE
  • RACEMIC DESOXY-NOR-EPHEDRINE
  • RAPHETAMINE
  • RHINALATOR
  • SIMPATEDRIN
  • SIMPATINA
  • SYMPAMINE
  • SYMPATEDRINE
  • WECKAMINE

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