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BENZENE, 1-(CHLOROMETHYL)-4-NITRO-

8 - Corrosive
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The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 100-14-1
DOT Hazard Label USCG CHRIS Code
  • Corrosive
none
NIOSH Pocket Guide International Chem Safety Card
none none
NFPA 704
data unavailable
General Description
Solid. (EPA, 1998)

The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
none
Air & Water Reactions
May react slowly with water. (NTP, 1992)
Fire Hazard
Incompatible with sodium hydroxide. (EPA, 1998)
Health Hazard
Poisonous if swallowed or dust is inhaled. (EPA, 1998)
Reactivity Profile
Incompatible with sodium hydroxide. [EPA, 1998]. A halogenated aromatic nitro compound. Aromatic nitro compounds range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction that culminates in a detonation. The aromatic nitro compounds may explode in the presence of a base such as sodium hydroxide or potassium hydroxide even in the presence of water or organic solvents. The explosive tendencies of aromatic nitro compounds are increased by the presence of multiple nitro groups.
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

Use caution: Liquids with this reactive group classification have been known to react with the absorbents listed below. More info about absorbents, including situations to watch out for...

  • Cellulose-Based Absorbents
  • Expanded Polymeric Absorbents

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)
Firefighting
Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. Wear self-contained (positive pressure if available) breathing apparatus and full protective clothing.

This material may burn but does not ignite readily. Small fires: dry chemical, carbon dioxide, water spray or foam. Large fires: Water spray, fog or foam. Move container from fire area if you can do it without risk. (EPA, 1998)
Non-Fire Response
Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. If water pollution occurs, notify appropriate authorities. Do not touch spilled material; stop leak if you can do so without risk.

Small spills: absorb with sand or other noncombustible absorbent material and place into containers for later disposal.

Small dry spills: with clean shovel, place material into clean, dry container and cover; move containers from spill area.

Large spills: dike far ahead of spill for alter disposal. (EPA, 1998)
Protective Clothing
For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Signs and Symptoms of Acute Benzene, 1-(Chloromethyl)-4-Nitro-Exposure: Signs and symptoms of acute exposure to benzene, 1-(chloromethyl)-4-nitro- may be severe and include cyanosis (blue tint to the skin and mucous membranes), tachycardia (rapid heart rate), hypotension (low blood pressure), and cardiac arrhythmias. Respiratory depression and respiratory failure may also occur. Headache, lethargy, weakness, vertigo (dizziness), severe depression, and coma may be noted. GI symptoms include nausea and vomiting. Urine and vomitus may have the odor of bitter almonds.

Emergency Life-Support Procedures: Acute exposure to benzene, 1-(chloromethyl)-4-nitro- may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to benzene, 1-(chloromethyl)-4-nitro.
2. Evaluate vital signs including pulse and respiratory rate and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.
4. Rush to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to benzene, 1-(chloromethyl)-4-nitro-.
2. Evaluate vital signs including pulse and respiratory rate and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas thoroughly with soap and water.
6. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.
7. Rush to a health care facility.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
3. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of benzene, 1-(chloromethyl)-4-nitro- is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
4. Ipecac should not be administered to children under 6 months of age. WARNING: Ingestion of benzene, 1-(chloromethyl)-4-nitro- may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should only be administered if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If there is ANY uncertainty, proceed to Step
4.The recommended dosages of Ipecac are: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
4. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 gm (1/2 to 1 oz) for children, 50 to 100 gm (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
5. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 gm (1/2 to 1 oz) of cathartic; 50 to 100 gm (1-3/4 to 3-1/2 oz) is recommended for adults.
6. Rush to a health care facility. (EPA, 1998)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds The information in CAMEO Chemicals comes from a variety of data sources.

Note: For Vapor Density and Specific Gravity, comparing the value to 1.0 can tell you if the chemical will likely sink/rise in air or sink/float in fresh water (respectively). Short phrases have been added to those values below as an aid. However, make sure to also consider the circumstances of a release. The Vapor Density comparisons are only valid when the gas escaping is at the same temperature as the surrounding air itself. If the chemical is escaping from a container where it was pressurized or refrigerated, it may first escape and behave as a heavy gas and sink in the air (even if it has a Vapor Density value less than 1). Also, the Specific Gravity comparisons are for fresh water (density 1.0 g/mL). If your spill is in salt water (density about 1.027 g/mL), you need to adjust the point of comparison. There are some chemicals that will sink in fresh water and float in salt water.
Chemical Formula:
  • C7H6ClNO2
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: 159.8°F (EPA, 1998)
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity: 1.5647 (NTP, 1992) - Denser than water; will sink
Boiling Point: data unavailable
Molecular Weight: 171.59 (EPA, 1998)
Water Solubility: Insoluble (NTP, 1992)
Ionization Energy/Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

Chemical PAC-1 PAC-2 PAC-3
Benzene, 1-(chloromethyl)-4-nitro-; (p-Nitrobenzyl chloride) (100-14-1) 2.5 mg/m3 28 mg/m3 360 mg/m3
(DOE, 2018)

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Cybersecurity and Infrastructure Security Agency's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
EPCRA 302
EHS TPQ
EPCRA 304
EHS RQ
CERCLA RQ EPCRA 313
TRI
RCRA
Code
CAA 112(r)
RMP TQ
Benzene, 1-(chloromethyl)-4-nitro- 100-14-1 500/10000 pounds 500 pounds

(EPA List of Lists, 2022)

CISA Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • ALPHA-CHLOR0-P-NITROTOLUENE
  • ALPHA-CHLORO-4-NITROTOLUENE
  • ALPHA-CHLORO-NITROTOLUENE
  • ALPHA-CHLORO-P-NITROTOLUENE
  • BENZENE, 1-(CHLOROMETHYL)-4-NITRO-
  • 1-(CHLOROMETHYL)-4-NITROBENZENE
  • 4-(CHLOROMETHYL)NITROBENZENE
  • 1-CHLOROMETHYL-4-NITROBENZENE
  • 4-NITROBENZYL CHLORIDE
  • 4-NITROPHENYLMETHYL CHLORIDE
  • P-(CHLOROMETHYL)NITROBENZENE
  • P-NITROBENZYL CHLORIDE
  • TOLUENE, ALPHA-CHLORO-P-NITRO-

Version 3.0.0