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2.3 - Poisonous gas 2.1 - Flammable gas
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The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 19287-45-7   (DIBORANE)
DOT Hazard Label USCG CHRIS Code
  • Poison Gas
  • Flammable Gas
NIOSH Pocket Guide International Chem Safety Card
Diboraneexternal link
NFPA 704
Diamond Hazard Value Description
4 3
Blue Health 4 Can be lethal.
Red Flammability 4 Burns readily. Rapidly or completely vaporizes at atmospheric pressure and normal ambient temperature.
Yellow Instability 3 Capable of detonation or explosive decomposition or explosive reaction but requires a strong initiating source or must be heated under confinement before initiation.
White Special W Reacts violently or explosively with water.
(NFPA, 2010)
General Description
Diborane is a colorless gas with an offensive odor. It is toxic by inhalation. Diborane is decomposed by water giving off hydrogen, another flammable gas and boric acid a non-regulated material. Its vapors are heavier than air. Long term exposure to low concentrations or short term exposure to high concentrations can result in adverse health effects from inhalation. It is used in electronics.

Rate of onset: Immediate

Persistence: Minutes to hours

Odor threshold: 2.5 ppm

Source/use/other hazard: Intermediate chemical manufacturing; very flammable.

The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
  • Strong Reducing Agent
  • Water-Reactive
  • Pyrophoric
Air & Water Reactions
Highly flammable. Ignites spontaneously in moist air (forms hydrogen and boric acid), [Haz. Chem. Data (1966)]. Oxygen and diborane form spontaneously explosive mixtures, [J. Amer. Chem. Soc. 76, 1997(1954)].
Fire Hazard
It will ignite spontaneously in moist air at room temperature. Also, it reacts violently with vaporizing liquid-type extinguishing agents. It hydrolyzes in water to hydrogen and boric acid. Incompatible with air, halogenated compounds, aluminum, lithium, active metals, oxidized surfaces, chlorine, fuming nitric acid, nitrogen trifluoride, oxygen, and phosphorus trifluoride. Avoid moist air, electrical sparks, open flames or any other heat source. Hazardous polymerization may occur. (EPA, 1998)
Health Hazard
Boranes are highly toxic by inhalation, skin absorption or ingestion. They may produce acute or chronic poisoning. Diborane is an irritant to the lungs and kidneys. The primary effect of diborane poisoning is lung congestion caused by local tissue irritation produced by the exothermic reaction of hydrolysis. (EPA, 1998)
Reactivity Profile
It is a colorless, air and moisture-sensitive gas, highly toxic. It ignites in air. It is very explosive when exposed to heat or flame, on contact with moisture it produces hydrogen gas. Explosive reaction with benzene vapor, chlorine, nitric acid and tetravinyllead [Bretherick, 5th ed., 1995, p. 77]. Explosive reaction with dimethyl sulfoxide [Shriver, 1969, p. 209], violent reaction with halocarbon liquids used as fire extinguishants (e.g., carbon tetrachloride). Reaction with Al or Li produces complex hydrides that may ignite spontaneously in air [Haz. Chem. Data, 1975, p. 114].
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
Excerpt from ERG Guide 119 [Gases - Toxic - Flammable]:

As an immediate precautionary measure, isolate spill or leak area for at least 100 meters (330 feet) in all directions.

SPILL: See ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 1911 datasheet.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 1600 meters (1 mile) in all directions; also, consider initial evacuation for 1600 meters (1 mile) in all directions. (ERG, 2016)
Firefighting should be done from an explosion-resistant location. Use water from unmanned monitors or hose holders to keep fire-exposed containers cool. If it is necessary to stop flow of gas, use water spray to protect personnel effecting shut-off. Personnel should be evacuated immediately. Self-contained breathing apparatus and full protective clothing should be worn. Isolate for 1/2 mile in all directions if tank car or truck is involved in fire.

Inert gas substances such as liquid nitrogen are recommended as fire extinguishing agents. (EPA, 1998)
Non-Fire Response
Excerpt from ERG Guide 119 [Gases - Toxic - Flammable]:

ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). All equipment used when handling the product must be grounded. Fully encapsulating, vapor-protective clothing should be worn for spills and leaks with no fire. Do not touch or walk through spilled material. Stop leak if you can do it without risk. Do not direct water at spill or source of leak. Use water spray to reduce vapors or divert vapor cloud drift. Avoid allowing water runoff to contact spilled material. FOR CHLOROSILANES, use AFFF alcohol-resistant medium-expansion foam to reduce vapors. If possible, turn leaking containers so that gas escapes rather than liquid. Prevent entry into waterways, sewers, basements or confined areas. Isolate area until gas has dispersed. (ERG, 2016)
Protective Clothing
Skin: No recommendation is made specifying the need for personal protective equipment for the body.

Eyes: No recommendation is made specifying the need for eye protection.

Wash skin: No recommendation is made specifying the need for washing the substance from the skin (either immediately or at the end of the work shift).

Remove: No recommendation is made specifying the need for removing clothing that becomes wet or contaminated.

Change: No recommendation is made specifying the need for the worker to change clothing after the work shift. (NIOSH, 2016)
DuPont Tychem® Suit Fabrics
Tychem® Fabric Legend
QS = Tychem 2000 SFR
QC = Tychem 2000
SL = Tychem 4000
C3 = Tychem 5000
TF = Tychem 6000
TP = Tychem 6000 FR
BR = Tychem 9000
TK = Tychem 10000
RF = Tychem 10000 FR
Testing Details
The fabric permeation data was generated for DuPont by independent testing laboratories using ASTM F739, EN369, EN 374-3, EN ISO 6529 (method A and B) or ASTM D6978 test methods. Normalized breakthrough times (the time at which the permeation rate is equal to 0.1 µg/cm2/min) reported in minutes. All liquid chemicals have been tested between approximately 20°C and 27°C unless otherwise stated. A different temperature may have significant influence on the breakthrough time; permeation rates typically increase with temperature. All chemicals have been tested at a concentration of greater than 95% unless otherwise stated. Unless otherwise stated, permeation was measured for single chemicals. The permeation characteristics of mixtures can deviate considerably from the permeation behavior of the individual chemicals. Chemical warfare agents (Lewisite, Sarin, Soman, Sulfur Mustard, Tabun and VX Nerve Agent) have been tested at 22°C and 50% relative humidity per military standard MIL-STD-282.
Normalized Breakthrough Times (in Minutes)
Chemical CAS Number State QS QC SL C3 TF TP BR RC TK RF
Diborane (10%) 19287-45-7 Vapor >480 >480 >480 >480
> indicates greater than.
A blank cell indicates the fabric has not been tested. The fabric may or may not offer barrier.

Special Warnings from DuPont

  1. Serged and bound seams are degraded by some hazardous liquid chemicals, such as strong acids, and should not be worn when these chemicals are present.
  2. CAUTION: This information is based upon technical data that DuPont believes to be reliable. It is subject to revision as additional knowledge and experience are gained. DuPont makes no guarantee of results and assumes no obligation or liability...
    ... in connection with this information. It is the user's responsibility to determine the level of toxicity and the proper personal protective equipment needed. The information set forth herein reflects laboratory performance of fabrics, not complete garments, under controlled conditions. It is intended for informational use by persons having technical skill for evaluation under their specific end-use conditions, at their own discretion and risk. Anyone intending to use this information should first verify that the garment selected is suitable for the intended use. In many cases, seams and closures have shorter breakthrough times and higher permeation rates than the fabric. Please contact DuPont for specific data. If fabric becomes torn, abraded or punctured, or if seams or closures fail, or if attached gloves, visors, etc. are damaged, end user should discontinue use of garment to avoid potential exposure to chemical. Since conditions of use are outside our control, we make no warranties, express or implied, including, without limitation, no warranties of merchantability or fitness for a particular use and assume no liability in connection with any use of this information. This information is not intended as a license to operate under or a recommendation to infringe any patent or technical information of DuPont or others covering any material or its use.

(DuPont, 2018)

First Aid
Warning: Effects may be delayed up to 24 hours. Caution is advised.

Signs and Symptoms of Acute Diborane Exposure: Signs and symptoms of acute exposure to diborane may include tightness in the chest, dyspnea (shortness of breath), cough, and wheezing. Nausea and pulmonary edema may also occur. Other possible effects of acute exposure include dizziness, headache, weakness, lack of coordination, muscle spasms, tremor, and seizures. Exposure to diborane may irritate or burn the skin, eyes, and mucous membranes.

Emergency Life-Support Procedures: Acute exposure to diborane may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to diborane.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. Transport to a health care facility.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self- exposure to diborane.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas at least twice with large amounts of cool water.
6. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
7. Transport to a health care facility.

Ingestion Exposure: No information is available. (EPA, 1998)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds The information in CAMEO Chemicals comes from a variety of data sources.
Chemical Formula:
  • B2H6
Flash Point: -130 ° F (EPA, 1998)
Lower Explosive Limit (LEL): 0.8 % (EPA, 1998)
Upper Explosive Limit (UEL): 88 % (EPA, 1998)
Autoignition Temperature: 100 to 126 ° F (NTP, 1992)
Melting Point: -265 ° F (EPA, 1998)
Vapor Pressure: 224 mm Hg at -169.6 ° F (EPA, 1998)
Vapor Density (Relative to Air): 1 (EPA, 1998)
Specific Gravity: 0.447 at -169.6 ° F (EPA, 1998)
Boiling Point: -135 ° F at 760 mm Hg (EPA, 1998)
Molecular Weight: 27.69 (EPA, 1998)
Water Solubility: Decomposes (NTP, 1992)
Ionization Potential: 11.38 eV (NIOSH, 2016)
IDLH: 15 ppm (NIOSH, 2016)

AEGLs (Acute Exposure Guideline Levels)

Final AEGLs for Diborane (19287-45-7)
Exposure Period AEGL-1 AEGL-2 AEGL-3
10 minutes NR 2 ppm 7.3 ppm
30 minutes NR 2 ppm 7.3 ppm
60 minutes NR 1 ppm 3.7 ppm
4 hours NR 0.25 ppm 0.92 ppm
8 hours NR 0.13 ppm 0.46 ppm
NR = Not recommended due to insufficient data
(NAC/NRC, 2017)

ERPGs (Emergency Response Planning Guidelines)

Chemical ERPG-1 ERPG-2 ERPG-3
Diborane (19287-45-7) NA 1 ppm 3 ppm
NA = not appropriate.
(AIHA, 2016)

PACs (Protective Action Criteria)

Chemical PAC-1 PAC-2 PAC-3
Diborane (19287-45-7) 0.3 ppm 1 ppm 3.7 ppm LEL = 8000 ppm
(DOE, 2016)

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Department of Homeland Security's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
CAA 112(r)
Diborane 19287-45-7 100 pounds 100 pounds 2500 pounds
Diborane(6) 19287-45-7 100 pounds 100 pounds 2500 pounds

(EPA List of Lists, 2015)

DHS Chemical Facility Anti-Terrorism Standards (CFATS)

Chemical of Interest CAS Number Min Conc STQ Security
Min Conc STQ Security
Min Conc STQ Security
Diborane 19287-45-7 1.00 % 2500 pounds toxic 2.67 % 15 pounds WME

(DHS, 2007)

OSHA Process Safety Management (PSM) Standard List

Chemical Name CAS Number Threshold Quantity (TQ)
Diborane 19287-45-7 100 pounds

(OSHA, 2011)

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • BORANE (B2H6)

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