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FLUOROACETAMIDE

6.1 - Poison
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The Chemical Identifier fields include common identification numbers, the NFPA diamond U.S. Department of Transportation hazard labels, and a general description of the chemical. The information in CAMEO Chemicals comes from a variety of data sources.
CAS Number UN/NA Number
  • 640-19-7
DOT Hazard Label USCG CHRIS Code
  • Poison
none
NIOSH Pocket Guide International Chem Safety Card
none
NFPA 704
data unavailable
General Description
Colorless crystalline powder. Used as a rodenticide. Highly toxic.

The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. The information in CAMEO Chemicals comes from a variety of data sources.
Reactivity Alerts
none
Air & Water Reactions
Very soluble in water [Farm Chemicals]
Fire Hazard
Emits very toxic fumes of fluorine containing compounds and nitrogen oxides when heated to decomposition. Avoid decomposing heat. (EPA, 1998)
Health Hazard
This material is super toxic; probable oral lethal dose in humans is less than 5 mg/kg, or a taste (less than 7 drops) for a 150-lb. person. Chemically inhibits oxygen metabolism by cells with critical damage occurring to the heart, brain, and lungs resulting in heart failure, respiratory arrest, convulsions, and death. (EPA, 1998)
Reactivity Profile
FLUOROACETAMIDE is a fluorinated amide. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents

No information available.

The Response Recommendation fields include isolation and evacuation distances, as well as recommendations for firefighting, non-fire response, protective clothing, and first aid. The information in CAMEO Chemicals comes from a variety of data sources.
Isolation and Evacuation
Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:

IMMEDIATE PRECAUTIONARY MEASURE: Isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.

SPILL: Increase the immediate precautionary measure distance, in the downwind direction, as necessary.

FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2020)
Firefighting
This compound is not very flammable but any fire involving this compound may produce dangerous vapors. You should evacuate the area. All firefighters should wear full-body protective clothing and use self-contained breathing apparatuses. You should extinguish any fires involving this chemical with a dry chemical, carbon dioxide, foam, or halon extinguisher. (NTP, 1992)
Non-Fire Response
Caution : Fluoroacetamide is extremely toxic. There is no known antidote. Immediately transport victims to a health care facility. Highly toxic fumes of fluorine-containing compounds and nitrogen oxides will be emitted when fluoroacetamide is heated to decomposition. Avoid sources of extreme heat including fire.

(Non-Specific -- Sodium Fluoroacetate) Do not touch spilled material; stop leak if you can do so without risk.

Small spills: absorb with sand or other non-combustible absorbent material and place into containers for later disposal.

Large spills: dike spill for later disposal. Keep unnecessary people away; isolate hazard area and deny entry. Stay upwind; keep out of low areas. (EPA, 1998)
Protective Clothing
For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
DuPont Tychem® Suit Fabrics
No information available.
First Aid
Warning: Effects usually appear within 30 minutes of exposure but may be delayed as long as 20 hours. Caution is advised. Vital signs should be monitored closely.

Signs and Symptoms of Acute Fluoroacetamide Exposure: Signs and symptoms may be extremely severe and range from nausea, vomiting, and diarrhea to convulsions, coma, and heart failure. Other symptoms include hyperactivity, respiratory depression or arrest, cyanosis (blue tint to the skin and mucous membranes), and ventricular fibrillation.

Emergency Life-Support Procedures: Acute exposure to fluoroacetamide may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.

Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to fluoroacetamide.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. RUSH to a health care facility.
4. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.

Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self- exposure to fluoroacetamide.
2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
3. Remove contaminated clothing as soon as possible.
4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
5. Wash exposed skin areas three times with soap and water.
6. RUSH to a health care facility.
7. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.

Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer oxygen or other respiratory support.
2. RUSH to a health care facility.
3. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures.
4. Vomiting may be induced with syrup of Ipecac. If elapsed time since ingestion of fluoroacetamide is unknown or suspected to be greater than 30 minutes, do not induce vomiting and proceed to Step
5.Ipecac should not be administered to children under 6 months of age.Warning: Ingestion of fluoroacetamide may result in sudden onset of seizures or loss of consciousness. Syrup of Ipecac should be administered only if victims are alert, have an active gag-reflex, and show no signs of impending seizure or coma. If ANY uncertainty exists, proceed to Step
5.The following dosages of Ipecac are recommended: children up to 1 year old, 10 mL (1/3 oz); children 1 to 12 years old, 15 mL (1/2 oz); adults, 30 mL (1 oz). Ambulate (walk) the victims and give large quantities of water. If vomiting has not occurred after 15 minutes, Ipecac may be readministered. Continue to ambulate and give water to the victims. If vomiting has not occurred within 15 minutes after second administration of Ipecac, administer activated charcoal.
5. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults. (EPA, 1998)

The Physical Property fields include properties such as vapor pressure and boiling point, as well as explosive limits and toxic exposure thresholds The information in CAMEO Chemicals comes from a variety of data sources.

Note: For Vapor Density and Specific Gravity, comparing the value to 1.0 can tell you if the chemical will likely sink/rise in air or sink/float in fresh water (respectively). Short phrases have been added to those values below as an aid. However, make sure to also consider the circumstances of a release. The Vapor Density comparisons are only valid when the gas escaping is at the same temperature as the surrounding air itself. If the chemical is escaping from a container where it was pressurized or refrigerated, it may first escape and behave as a heavy gas and sink in the air (even if it has a Vapor Density value less than 1). Also, the Specific Gravity comparisons are for fresh water (density 1.0 g/mL). If your spill is in salt water (density about 1.027 g/mL), you need to adjust the point of comparison. There are some chemicals that will sink in fresh water and float in salt water.
Chemical Formula:
  • C2H4FNO
Flash Point: data unavailable
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point: 225 to 228°F (EPA, 1998)
Vapor Pressure: data unavailable
Vapor Density (Relative to Air): data unavailable
Specific Gravity: data unavailable
Boiling Point: Sublimes on heating (EPA, 1998)
Molecular Weight: 77.06 (EPA, 1998)
Water Solubility: data unavailable
Ionization Energy/Potential: data unavailable
IDLH: data unavailable

AEGLs (Acute Exposure Guideline Levels)

No AEGL information available.

ERPGs (Emergency Response Planning Guidelines)

No ERPG information available.

PACs (Protective Action Criteria)

Chemical PAC-1 PAC-2 PAC-3
Fluoroacetamide (640-19-7) 0.53 mg/m3 5.8 mg/m3 19 mg/m3
(DOE, 2018)

The Regulatory Information fields include information from the U.S. Environmental Protection Agency's Title III Consolidated List of Lists, the U.S. Cybersecurity and Infrastructure Security Agency's Chemical Facility Anti-Terrorism Standards, and the U.S. Occupational Safety and Health Administration's Process Safety Management of Highly Hazardous Chemicals Standard List (see more about these data sources).

EPA Consolidated List of Lists

Regulatory Name CAS Number/
313 Category Code
EPCRA 302
EHS TPQ
EPCRA 304
EHS RQ
CERCLA RQ EPCRA 313
TRI
RCRA
Code
CAA 112(r)
RMP TQ
Fluoroacetamide 640-19-7 100/10000 pounds 100 pounds 100 pounds P057

(EPA List of Lists, 2022)

CISA Chemical Facility Anti-Terrorism Standards (CFATS)

No regulatory information available.

OSHA Process Safety Management (PSM) Standard List

No regulatory information available.

This section provides a listing of alternate names for this chemical, including trade names and synonyms.
  • 1081
  • ACETAMIDE, 2-FLUORO-
  • AFL 1081
  • ALPHA-FLUOROACETAMIDE
  • COMPOUND 1081
  • FAA
  • FLUORAKIL 100
  • FLUOROACETAMIDE
  • 2-FLUOROACETAMIDE
  • FLUOROACETIC ACID AMIDE
  • FLUTRITEX 1
  • FUSSOL
  • MEGATOX
  • MONOFLUOROACETAMIDE
  • NAVRON
  • RODEX
  • YANOCK

Version 3.0.0