SARIN
The
Chemical Identifier fields
include common identification numbers, the
NFPA diamond
U.S. Department of Transportation hazard labels, and a general
description of the chemical. The information in CAMEO Chemicals comes
from a variety of
data sources.
| CAS Number | UN/NA Number |
|---|---|
|
|
| DOT Hazard Label | USCG CHRIS Code |
|
none |
| NIOSH Pocket Guide | International Chem Safety Card |
| none | none |
NFPA 704
data unavailable
General Description
A colorless, odorless liquid. Almost no odor in pure state. Used as a quick-acting military chemical nerve agent. Chemical warfare agent.
The
Hazard fields
include
special hazard alerts
air and water
reactions, fire hazards, health hazards, a reactivity profile, and
details about
reactive groups assignments
and
potentially incompatible absorbents.
The information in CAMEO Chemicals comes from a variety of
data sources.
Reactivity Alerts
- Water-Reactive
Air & Water Reactions
Hydrolyzed by water to form hydrogen fluoride and the nontoxic phosphonic acid derivative. It is rapidly hydrolyzed by dilute aqueous sodium hydroxide [Merck 11th ed. 1989].
Fire Hazard
Non-flammable. Acidic conditions produce hydrogen fluoride; alkaline conditions produce isopropyl alcohol and polymers. When heated to decomposition or reacted with steam, it emits very toxic fumes of fluorides and oxides of phosphorus. Slightly corrosive to steel. Hydrolyzed by water. (EPA, 1998)
Health Hazard
Extremely toxic; lethal dose in humans may be as low as 0.01 mg/kg. Extremely active cholinesterase inhibitor. Toxic effects similar to, but more severe than those of parathion. Death within 15 minutes after fatal dose is absorbed. (EPA, 1998)
Reactivity Profile
Acidic conditions produce hydrogen fluoride; alkaline conditions produce isopropyl alcohol and polymers. When heated to decomposition or reacted with steam, it emits very toxic fumes of fluorides and oxides of phosphorus. Slightly corrosive to steel. Hydrolyzed by water [EPA, 1998].
Belongs to the Following Reactive Group(s)
Potentially Incompatible Absorbents
Use caution: Liquids with this reactive group classification have been known to react with the absorbents listed below. More info about absorbents, including situations to watch out for...
- Cellulose-Based Absorbents
- Mineral-Based & Clay-Based Absorbents
- Dirt/Earth
The
Response Recommendation fields
include isolation and evacuation distances, as well as recommendations for
firefighting, non-fire response, protective clothing, and first aid. The
information in CAMEO Chemicals comes from a variety of
data sources.
Isolation and Evacuation
Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]:
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
SPILL: If this material is being used as a weapon, see ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 2810 datasheet. Otherwise increase, in the downwind direction, as necessary, the isolation distance shown above.
FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids.
SPILL: If this material is being used as a weapon, see ERG Table 1 - Initial Isolation and Protective Action Distances on the UN/NA 2810 datasheet. Otherwise increase, in the downwind direction, as necessary, the isolation distance shown above.
FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
Firefighting
Protective clothing and respiratory protection.
Extinguish with foam, carbon dioxide, and dry chemical (EPA, 1998)
Extinguish with foam, carbon dioxide, and dry chemical (EPA, 1998)
Non-Fire Response
Rapidly hydrolyzed by dilute aqueous sodium hydroxide or sodium carbonate forming relatively non-toxic products. Water alone removes the fluorine atom producing a non-toxic acid. Decontaminants include bleach slurry, dilute alkali, hot soapy water, steam and ammonia. (EPA, 1998)
Protective Clothing
For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
DuPont Tychem® Suit Fabrics
Tychem® Fabric Legend
| QS = Tychem 2000 SFR |
| QC = Tychem 2000 |
| SL = Tychem 4000 |
| C3 = Tychem 5000 |
| TF = Tychem 6000 |
| TP = Tychem 6000 FR |
| BR = Tychem 9000 |
| RC = Tychem RESPONDER® CSM |
| TK = Tychem 10000 |
| RF = Tychem 10000 FR |
Testing Details
The fabric permeation data was generated for DuPont by independent
testing laboratories using ASTM F739, EN369, EN 374-3, EN ISO 6529
(method A and B) or ASTM D6978 test methods.
Normalized breakthrough times
(the time at which the permeation rate is equal to 0.1 µg/cm2/min)
reported in minutes.
All liquid chemicals have been tested between approximately 20°C and
27°C unless otherwise stated.
A different temperature may have significant influence on the
breakthrough time; permeation rates typically increase with
temperature.
All chemicals have
been tested at a concentration of greater than 95% unless otherwise
stated.
Unless otherwise stated, permeation was measured for single chemicals.
The permeation characteristics of mixtures can deviate considerably
from the permeation behavior of the individual chemicals.
Chemical warfare agents (Lewisite, Sarin, Soman, Sulfur
Mustard, Tabun and VX Nerve Agent) have been tested at 22°C and 50%
relative humidity per military standard MIL-STD-282.
| Chemical | CAS Number | State | QS | QC | SL | C3 | TF | TP | BR | RC | TK | RF |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sarin (>95%, 10 g/m² coverage) | 107-44-8 | Liquid | >480 | 120 | >480 | >480 | >480 | >480 | ||||
| Sarin (>95%, 100 g/m² coverage) | 107-44-8 | Liquid | >480 | >480 | >480 | >480 | >480 | >480 |
> indicates greater than.
A blank cell indicates the fabric has not been tested. The fabric may or may not offer barrier.
A blank cell indicates the fabric has not been tested. The fabric may or may not offer barrier.
Special Warnings from DuPont
- Serged and bound seams are degraded by some hazardous liquid chemicals, such as strong acids, and should not be worn when these chemicals are present.
-
CAUTION: This information is based upon technical data that
DuPont believes to be reliable. It is subject to revision as
additional knowledge and experience are gained. DuPont makes no
guarantee of results and assumes no obligation or liability...
... in connection with this information. It is the user's responsibility to determine the level of toxicity and the proper personal protective equipment needed. The information set forth herein reflects laboratory performance of fabrics, not complete garments, under controlled conditions. It is intended for informational use by persons having technical skill for evaluation under their specific end-use conditions, at their own discretion and risk. Anyone intending to use this information should first verify that the garment selected is suitable for the intended use. In many cases, seams and closures have shorter breakthrough times and higher permeation rates than the fabric. Please contact DuPont for specific data. If fabric becomes torn, abraded or punctured, or if seams or closures fail, or if attached gloves, visors, etc. are damaged, end user should discontinue use of garment to avoid potential exposure to chemical. Since conditions of use are outside our control, we make no warranties, express or implied, including, without limitation, no warranties of merchantability or fitness for a particular use and assume no liability in connection with any use of this information. This information is not intended as a license to operate under or a recommendation to infringe any patent or technical information of DuPont or others covering any material or its use.
(DuPont, 2018)
First Aid
Note: Sarin is an EXTREMELY ACTIVE cholinesterase inhibitor. Warning: Death may occur within 1 to 10 minutes of inhalation exposure to a minute amount of sarin. Immediate decontamination of the smallest drop is essential. Effects may be delayed with dermal exposure. Extreme caution is advised.
Signs and Symptoms of Sarin Exposure: The first indication of exposure to sarin may be a reaction at the point of contact: localized sweating, muscular twitching, and pinpoint eye pupils. Rhinorrhea (running nose), tightness of the chest with shortness of breath, and dimness of vision may be noted. In more severe exposure, headache, cramps, nausea, vomiting, involuntary defecation and urination, twitching, jerking, staggering, convulsions, drowsiness, coma, and respiratory arrest may be seen.
Emergency Life-Support Procedures: Acute exposure to sarin may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to sarin.
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. DO NOT perform mouth-to-mouth resuscitation when facial contamination exists; use forced-oxygen mask. If breathing is labored, administer oxygen or other respiratory support.
4. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to sarin.
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. DO NOT perform mouth-to-mouth resuscitation when facial contamination exists; use forced-oxygen mask.
4. Remove and isolate contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
6. Wash exposed skin areas thoroughly with commercial household liquid bleach and then flush with water. Avoid contacting the eyes or mouth with bleach.
7. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. DO NOT perform mouth-to-mouth resuscitation when facial contamination exists; use forced-oxygen mask. If breathing is labored, administer oxygen or other respiratory support.
2. RUSH to a health care facility!
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. DO NOT induce vomiting or attempt to neutralize.
5. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults. (EPA, 1998)
Signs and Symptoms of Sarin Exposure: The first indication of exposure to sarin may be a reaction at the point of contact: localized sweating, muscular twitching, and pinpoint eye pupils. Rhinorrhea (running nose), tightness of the chest with shortness of breath, and dimness of vision may be noted. In more severe exposure, headache, cramps, nausea, vomiting, involuntary defecation and urination, twitching, jerking, staggering, convulsions, drowsiness, coma, and respiratory arrest may be seen.
Emergency Life-Support Procedures: Acute exposure to sarin may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination.
Inhalation Exposure:
1. Move victims to fresh air. Emergency personnel should avoid self-exposure to sarin.
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. DO NOT perform mouth-to-mouth resuscitation when facial contamination exists; use forced-oxygen mask. If breathing is labored, administer oxygen or other respiratory support.
4. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
Dermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-exposure to sarin.
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. DO NOT perform mouth-to-mouth resuscitation when facial contamination exists; use forced-oxygen mask.
4. Remove and isolate contaminated clothing as soon as possible.
5. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes.
6. Wash exposed skin areas thoroughly with commercial household liquid bleach and then flush with water. Avoid contacting the eyes or mouth with bleach.
7. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
Ingestion Exposure:
1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. DO NOT perform mouth-to-mouth resuscitation when facial contamination exists; use forced-oxygen mask. If breathing is labored, administer oxygen or other respiratory support.
2. RUSH to a health care facility!
3. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures.
4. DO NOT induce vomiting or attempt to neutralize.
5. Activated charcoal may be administered if victims are conscious and alert. Use 15 to 30 g (1/2 to 1 oz) for children, 50 to 100 g (1-3/4 to 3-1/2 oz) for adults, with 125 to 250 mL (1/2 to 1 cup) of water.
6. Promote excretion by administering a saline cathartic or sorbitol to conscious and alert victims. Children require 15 to 30 g (1/2 to 1 oz) of cathartic; 50 to 100 g (1-3/4 to 3-1/2 oz) is recommended for adults. (EPA, 1998)
The
Physical Property fields
include properties such as vapor pressure and
boiling point, as well as explosive limits and
toxic exposure thresholds
The information in CAMEO Chemicals comes from a variety of
data sources.
| Chemical Formula: |
|
Flash Point:
Non-flammable
(EPA, 1998)
Lower Explosive Limit (LEL): data unavailable
Upper Explosive Limit (UEL): data unavailable
Autoignition Temperature: data unavailable
Melting Point:
-71 ° F
(EPA, 1998)
Vapor Pressure:
2.9 mm Hg
at 77 ° F
(EPA, 1998)
Vapor Density (Relative to Air):
4.86
(EPA, 1998)
Specific Gravity:
1.1
at 68 ° F
(EPA, 1998)
Boiling Point:
297 ° F
at 760 mm Hg
(EPA, 1998)
Molecular Weight:
140.11
(EPA, 1998)
Water Solubility: data unavailable
Ionization Potential: data unavailable
IDLH: data unavailable
AEGLs (Acute Exposure Guideline Levels)
| Exposure Period | AEGL-1 | AEGL-2 | AEGL-3 |
|---|---|---|---|
| 10 minutes | 0.0012 ppm | 0.015 ppm | 0.064 ppm |
| 30 minutes | 0.00068 ppm | 0.0085 ppm | 0.032 ppm |
| 60 minutes | 0.00048 ppm | 0.006 ppm | 0.022 ppm |
| 4 hours | 0.00024 ppm | 0.0029 ppm | 0.012 ppm |
| 8 hours | 0.00017 ppm | 0.0022 ppm | 0.0087 ppm |
(NAC/NRC, 2017)
ERPGs (Emergency Response Planning Guidelines)
No ERPG information available.PACs (Protective Action Criteria)
| Chemical | PAC-1 | PAC-2 | PAC-3 |
|---|---|---|---|
| Agent GB; (Sarin, Isopropyl methanefluoro-phosphonate) (107-44-8) | 0.00048 ppm | 0.006 ppm | 0.022 ppm |
(DOE, 2016)
The
Regulatory Information fields
include information from
the U.S. Environmental Protection Agency's Title III Consolidated List of
Lists,
the U.S. Department of Homeland Security's Chemical Facility
Anti-Terrorism Standards,
and the U.S. Occupational Safety and Health Administration's
Process Safety Management of Highly Hazardous Chemicals Standard List
(see more about these
data sources).
EPA Consolidated List of Lists
| Regulatory Name | CAS Number/ 313 Category Code |
EPCRA 302 EHS TPQ |
EPCRA 304 EHS RQ |
CERCLA RQ | EPCRA 313 TRI |
RCRA Code |
CAA 112(r) RMP TQ |
|---|---|---|---|---|---|---|---|
| Sarin | 107-44-8 | 10 pounds | 10 pounds |
(EPA List of Lists, 2015)
DHS Chemical Facility Anti-Terrorism Standards (CFATS)
| RELEASE | THEFT | SABOTAGE | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Chemical of Interest | CAS Number | Min Conc | STQ | Security Issue |
Min Conc | STQ | Security Issue |
Min Conc | STQ | Security Issue |
| Sarin; [o-Isopropyl methylphosphonofluoridate] | 107-44-8 | CUM 100 grams | CW/CWP | |||||||
- CW/CWP = chemical weapons/chemical weapons precursors.
- CUM = cumulative.
(DHS, 2007)
OSHA Process Safety Management (PSM) Standard List
| Chemical Name | CAS Number | Threshold Quantity (TQ) |
|---|---|---|
| Sarin | 107-44-8 | 100 pounds |
(OSHA, 2011)
This section provides a listing of alternate names for this chemical,
including trade names and synonyms.
- GB
- GB (CHEMICAL WARFARE AGENT)
- IMPF
- ISOPROPOXYMETHYLPHOSPHORYL FLUORIDE
- ISOPROPYL METHANEFLUOROPHOSPHONATE
- ISOPROPYL METHYLFLUOROPHOSPHATE
- ISOPROPYL METHYLFLUOROPHOSPHONATE
- ISOPROPYL METHYLPHOSPHONOFLUORIDATE
- ISOPROPYL-METHYL-PHOSPHORYL FLUORIDE
- 1-METHYLETHYL METHYLPHOSPHONOFLUORIDATE
- METHYLFLUOROPHOSPHORIC ACID ISOPROPYL ESTER
- METHYLPHOSPHONOFLUORIDIC ACID ISOPROPYL ESTER
- MFI
- O-ISOPROPYL METHYLFLUOROPHOSPHONATE
- O-ISOPROPYL METHYLPHOSPHONOFLUORIDATE
- PHOSPHINE OXIDE, FLUOROISOPROPOXYMETHYL
- PHOSPHONOFLUORIDIC ACID, METHYL-, ISOPROPYL ESTER
- PHOSPHORIC ACID, METHYLFLUORO-, ISOPROPYL ESTER
- SARIN
- SARIN II
- T-144
- T-2106
- TL 1618
- TRILONE 46
Version 2.7.1 rev 3